Clinical Providers
Expanding treatment options for patients with type 2 diabetes
Rethinking the duodenum’s role as a therapeutic target
There is a critical, yet often overlooked, opportunity to bring about positive therapeutic changes in the metabolic system of individuals with type 2 diabetes.7,8 Research shows that this opportunity may lie within the critically important yet malfunctioning cells and signaling pathways within the small intestine (duodenum) of individuals with type 2 diabetes.9
The ability to selectively target and physiologically restore critical signaling mechanisms in the duodenum makes it a meaningful therapeutic target. This physiologic restoration aims to reset the signaling pathways, potentially reestablishing proper communication between the duodenum and other organs involved in metabolic functions. This could significantly enhance the body’s ability to manage glucose levels effectively and limit disease progression.
Endogenex is committed to improving the treatment of type 2 diabetes
The ReCET Procedure is investigational and currently being evaluated in clinical study.
Endogenex is focused on shifting the treatment paradigm for people living with type 2 diabetes. Current diabetes care focuses on the downstream consequences of this metabolic disease by targeting insulin resistance with medications and insulin replacement therapy.
Endogenex’s goal is to reset the cellular signaling of the duodenum to help the body better manage blood sugar levels, reduce or eliminate dependence on drug-based treatments, enhance existing therapies, and potentially slow the progression of the disease.
Endogenex’s ReCET System applies the principle of resetting the metabolic operating system by eliminating poorly functioning signaling cells and inducing regrowth of healthy signaling cells in the duodenum. ReCET’s application of non-thermal, pulsed electric fields to the mucosa and submucosal duodenal tissue aims to regenerate targeted cells without disturbing the extracellular matrix.
Regeneration of these cells is intended to restore proper metabolic signaling, improve the body’s ability to manage blood glucose levels, and potentially slow disease progression.
The ReCET Procedure
ReCET is a novel, endoscopic outpatient procedure that takes approximately an hour to complete. The patient is discharged the same day.
“This [ReCET Procedure] could be a tremendous opportunity for people to have an outpatient, simple endoscopic procedure and be able to control their diabetes.”
Paul Severson, M.D.
Cuyuna Regional Medical Center
ReCET Clinical Study
Endogenex is sponsoring the ReCET Clinical Study at sites in the United States and Australia. Learn about the ReCET Study and how you can get involved.